[green-goblin]

High all,

I have a thermally stable polymer with side chains containing GFLG peptide linkers. I need to remove some DMSO from the reaction mixture and was hoping someone could tell me how thermally stable this peptide linker  is likely to be (or just the general thermal stability of peptides).

At the moment I have the flask on a high vac line and am heating it at only 40 degree so it is taking quite a while.

Cheers,

C

[green-goblin]

Ah, I just read that breaking peptide bonds without an enzyme requires boiling in 6M HCl for 24 hours so I should be alright to take the temp a little higher.