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Topic: Discuss this statement and give reasons and examples.  (Read 8014 times)

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Offline Joniaguis

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Discuss this statement and give reasons and examples.
« on: January 03, 2009, 08:51:23 AM »
Gas liquid chromatography (GLC) and High Performance Liquid Chromatogra[hy (HPLC), analytical techniques used for qualitative and quantitative analysis of drugs, complement each other.


What do you think?
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Offline Arkcon

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Re: Discuss this statement and give reasons and examples.
« Reply #1 on: January 03, 2009, 09:00:44 AM »
The bit in boldface, why is that so?  What supporting facts can you offer?
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Hey, I'm not judging.  I just like to shoot straight.  I'm a man of science.

Offline JGK

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Re: Discuss this statement and give reasons and examples.
« Reply #2 on: January 03, 2009, 07:40:07 PM »
Think about the basics of each technique and whether they contrast or complement each other and go from there.
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Offline Joniaguis

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Re: Discuss this statement and give reasons and examples.
« Reply #3 on: January 04, 2009, 01:56:51 PM »
ok thanks a lot  :)

retention time, area of peak, detector are among the similarities
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Offline Telamond

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Re: Discuss this statement and give reasons and examples.
« Reply #4 on: January 04, 2009, 05:21:07 PM »
I don't think that the retention time, area of peak and detectors are the same for GC and HPLC.

Think of what type of sample that are suited for HPLC resp. GC.
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Offline NP1957

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Re: Discuss this statement and give reasons and examples.
« Reply #5 on: January 05, 2009, 04:53:52 AM »
I agree with JGK to think about the basics.

GLC injection system needs high temperature while HPLC doesn't. For samples which are thermally unstable and very difficult to vapourize, HPLC is preference.

GLC offers more variety of liquid stationary phase, therefore GLC may provide a better separation for some sample which HPLC couldn't.
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