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Topic: Addition of water to a Grignard reaction  (Read 6188 times)

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Offline lucas89

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Addition of water to a Grignard reaction
« on: March 25, 2009, 08:07:07 PM »
I'm aware of what happens when water is added to the reaction mixture in a grignard synthesis at the point before you add your ketone, with Mg(OH)Br being formed. Now, with my lab exam coming up in one week, I figured a nice question my instructor could possibly ask is what would happen to the reaction mixture if water is introduced to the mixture at the point after the ketone is added (but before the adition of the strong acid).

I've thought about it for a while, but I can't think of an answer. Anyone have a possible idea?

Offline CopperSmurf

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Re: Addition of water to a Grignard reaction
« Reply #1 on: March 25, 2009, 10:43:54 PM »
I don't think anything would happen to your product. It'll probably just react with your excess grignard reagent before disposal.

Offline lucas89

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Re: Addition of water to a Grignard reaction
« Reply #2 on: March 26, 2009, 03:59:15 PM »
Yeah, I asked my instructor today. He said that our desired product would be formed, however some Mg(OH)2 could also be formed, which would be difficult to separate from the reaction mixture.

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