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protection of the carbonyl of an enone
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Topic: protection of the carbonyl of an enone (Read 4061 times)
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g-bones
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protection of the carbonyl of an enone
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on:
August 28, 2009, 04:38:22 PM »
I am reviewing some problems and I have the attached problem in which i am given the starting material and the reagents and must predict the product. when I first looked at it I didn't think much and came up with the reaction path and the product shown. the only thing I am worried about is whether the formation of the acetal will be productive or whether a michael addition would occur instead thus destroying the double bond and not giving the ozone anything to react with. anybody have any thoughts.
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Arctic-Nation
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Posts: 265
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Re: protection of the carbonyl of an enone
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Reply #1 on:
August 30, 2009, 04:45:18 PM »
I don't really expect any problems. Some side reactions might occur, but oxygen loves hard-hard interactions, so glycol addition should only happen at the carbonyl-carbon, not at the beta-position.
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protection of the carbonyl of an enone