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Topic: Function of MeOH in reducing ketone to alcohol with NaBH4  (Read 7878 times)

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Offline Fmeub

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Function of MeOH in reducing ketone to alcohol with NaBH4
« on: December 07, 2009, 12:53:34 PM »
Hi!

I reduced a ketone to an alcohol with NaBH4. I thought that methanol was just the solvent, but it seems it has more of a function than that. Also, I put Ce(III)Cl3 in the pot. What is the function of Ce(III) chloride?

Thanks!
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Offline Telamond

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Re: Function of MeOH in reducing ketone to alcohol with NaBH4
« Reply #1 on: December 07, 2009, 12:57:51 PM »
Oh! I did this reaction recently! =)
It's a Luche reduction.

Everything you need to know is available here:
http://en.wikipedia.org/wiki/Luche_reduction
http://www.organic-chemistry.org/namedreactions/luche-reduction.shtm
and their article:

Gemal, André. Luche, Jean-Louis. Journal of American Chemical Society, 1981, 103, 5454-5459.
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Offline Fmeub

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Re: Function of MeOH in reducing ketone to alcohol with NaBH4
« Reply #2 on: December 09, 2009, 03:07:28 AM »
Thank you very much.

Your references have helped me a lot!

 ;D
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