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Topic: Oximes to N-hydroxy amines  (Read 2526 times)

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Offline JeffG

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Oximes to N-hydroxy amines
« on: July 19, 2010, 05:56:57 PM »
Hello.

I wonder if any in here have any ways to reduce an oxime to a N-hydroxy amine? Will NaBH4 be strong enough or should I go through cyanoborohydride maybe?

Any suggestion are welcome. I am just afraid of no reaction or maybe reduce to the amine.

Thank in advance.

Jeff

Offline Jorriss

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Re: Oximes to N-hydroxy amines
« Reply #1 on: July 19, 2010, 06:59:22 PM »
Sodium cyanoborohydride might do the trick. It's a mild reducing agent often used on imines.

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