[messiah028]

hi just a quick question abt a NMR problem

if say metabolite 1 on treatment with enzyme B-glucuronidase gave a substance identical to metabolite 2 by chromotography, mass spectra and H-NMR pectra does that mean metabolite 1 is a glucuronide ion of metabolite 2?

[discodermolide]

hi just a quick question abt a NMR problem

if say metabolite 1 on treatment with enzyme B-glucuronidase gave a substance identical to metabolite 2 by chromotography, mass spectra and H-NMR pectra does that mean metabolite 1 is a glucuronide ion of metabolite 2?

No, it does not mean that, what else can happen?

[messiah028]

im not sure
i thought metaboilte 1 would be a glucuronide ion

[discodermolide]

im not sure
i thought metaboilte 1 would be a glucuronide ion

If everything is identical chromatography, NMR etc perhaps the new compound is an enantiomer of the first one?