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Topic: Deprotect Cbz in the presence of Alloc?  (Read 5222 times)

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Offline tak

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Deprotect Cbz in the presence of Alloc?
« on: November 05, 2010, 03:51:57 PM »
Can you deprotect Cbz in the presence of Alloc? Using, say TMSI or HBr in AcOH? Thanks!
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Offline MissPhosgene

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Re: Deprotect Cbz in the presence of Alloc?
« Reply #1 on: November 12, 2010, 04:25:36 PM »
I'm pretty sure you will cleave both under those conditions. Try looking at the reactivity charts in Green's Protective Groups.
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