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Topic: about michael addition experiment  (Read 5533 times)

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Offline glock17

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about michael addition experiment
« on: April 10, 2011, 05:42:54 AM »
i have been working on a Michael addition experiment.
And i have difficulty in finding the structure of its product
can someone help me please
the name of my product is
1-Phenyl-3-phenylaminopyrrolidine-2, 5-dione
thanks a lot ;D

Offline sjb

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Re: about michael addition experiment
« Reply #1 on: April 10, 2011, 06:01:07 AM »
i have been working on a Michael addition experiment.
And i have difficulty in finding the structure of its product
can someone help me please
the name of my product is
1-Phenyl-3-phenylaminopyrrolidine-2, 5-dione
thanks a lot ;D

What is the structure of pyrrolidine? Of pyrrolidine-2,5-dione? ...

Or alternatively, what reactions did you carry out, perhaps we can build the structure up that way?

Offline glock17

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Re: about michael addition experiment
« Reply #2 on: April 10, 2011, 06:49:31 AM »
the experiment consist of two step
first prepare Maleanilic acid by the following reactant

maleic anhydride (3g, 30 mmol) and aniline (3g, 32 mmol) in glacial
acetic acid (15 ml) for 30 min. at room temperature

second step:
Reflux the mixture of aniline (1g, 11 mmol), crude maleanilic acid (A) from the above
preparation (2g, 10 mmol) and glacial acetic acid (10 ml) for 30 min.
then 1-Phenyl-3-phenylaminopyrrolidine-2, 5-dione is obtained

Offline glock17

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Re: about michael addition experiment
« Reply #3 on: April 10, 2011, 07:38:08 AM »


What is the structure of pyrrolidine? Of pyrrolidine-2,5-dione? ...

Or alternatively, what reactions did you carry out, perhaps we can build the structure up that way?
[/quote]
i think i come up a structure according to your method

http://www.chemspider.com/ImageView.aspx?id=9588625
and by adding carbonly group to the two carbon near to the nirtogen ring
thx i think i got it~ ;D

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