[quietone]

How would I combine a benzene ring and a cyclohexane? I can't break any of the benzene ring's double bonds, and the two molecules will be sharing two carbons. I know if it was just a hexane chain I was adding, I could use a Friedel Crafts alkylation, but I'm lost as to how to do it with a cyclic molecule.

[Vidya]

whats the problem with the cyclohexane ?
you can use this also in friedel crafts alkylation reaction

[discodermolide]

How would I combine a benzene ring and a cyclohexane? I can't break any of the benzene ring's double bonds, and the two molecules will be sharing two carbons. I know if it was just a hexane chain I was adding, I could use a Friedel Crafts alkylation, but I'm lost as to how to do it with a cyclic molecule.

Try hydrogenation of naphthalene at low temperature,

[quietone]

@discodermolide I have to start with a benzene, and make the tetralin molecule, so I can't use the naphthalene. @Uma How would I do the alkylation? Could I hypothetically place a Cl at the 1 and 2 positions on the cyclohexane and then run the normal alkylation?

[sjb]

@discodermolide I have to start with a benzene, and make the tetralin molecule, so I can't use the naphthalene. @Uma How would I do the alkylation? Could I hypothetically place a Cl at the 1 and 2 positions on the cyclohexane and then run the normal alkylation?

Not an alkylation, but what other forms of Friedel-Crafts do you know?

[quietone]

@sjb I only know two forms, alkylation and acylation. I didn't know there were more than that.

[contra]

@quietone

Look into using acylation and Clemmenson reductions. The synthesis is only a few steps, you can do it!

[BluePill]

suzuki coupling is a good coupling reaction.