September 23, 2024, 11:28:37 PM
Forum Rules: Read This Before Posting


« previous next »
Pages: [1]   Go Down

Topic: SYNTHESIS of Ph-COOH to Ph-CH2-COOH  (Read 5604 times)

0 Members and 1 Guest are viewing this topic.

Offline miss_science

  • New Member
  • **
  • Posts: 4
  • Mole Snacks: +0/-0
SYNTHESIS of Ph-COOH to Ph-CH2-COOH
« on: July 30, 2011, 11:28:10 PM »
What kind of synthesis should I look into? I just wanna get guided to the right direction. Thanks!
Logged

Offline asa029

  • Regular Member
  • ***
  • Posts: 64
  • Mole Snacks: +1/-0
Re: SYNTHESIS of Ph-COOH to Ph-CH2-COOH
« Reply #1 on: July 31, 2011, 05:09:46 AM »
You're building carbon skeleton by adding one extra carbon. You should therefore look into carbon-elongation reactions. I immediately think a simple Grignard with some functional group transformations should do the trick.
Logged

Offline Åke

  • Regular Member
  • ***
  • Posts: 55
  • Mole Snacks: +4/-0
Re: SYNTHESIS of Ph-COOH to Ph-CH2-COOH
« Reply #2 on: July 31, 2011, 09:17:48 AM »
Miss Science,  :D

Interesting question - try Arndt-Eisert homologation: http://en.wikipedia.org/wiki/Arndt%E2%80%93Eistert_reaction
Logged
Pages: [1]   Go Up
« previous next »
Sponsored Links