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Topic: question involving synthesis of a di-substituted benzene  (Read 3326 times)

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Offline natel8484

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question involving synthesis of a di-substituted benzene
« on: March 13, 2008, 07:34:26 PM »
The question asks to start with benzene and add a tert-butyl group and a nitro group meta to each other. I know i cant add the nitro group first and do a friedel-crafts because the nitro is too deactivating. I was thinking of adding the tert-butyl by friedel-crafts akylation first but then didn't know how to add the nitro group considering the tert-butyl is an o/p director. Any advice?

Edit* Nevermind, just figured it out.

« Last Edit: March 13, 2008, 08:26:52 PM by natel8484 »

Offline agrobert

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Re: question involving synthesis of a di-substituted benzene
« Reply #1 on: March 13, 2008, 08:48:31 PM »
Whats your solution?  If you start a thread you should finish it.
In the realm of scientific observation, luck is only granted to those who are prepared. -Louis Pasteur

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