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What nucleotide is mU in tRNA?
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Topic: What nucleotide is mU in tRNA? (Read 2719 times)
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brasarehot
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What nucleotide is mU in tRNA?
«
on:
February 23, 2012, 09:01:09 AM »
isn't it methyluridine, but what atom is methylated? Thanks.
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Arkcon
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Re: What nucleotide is mU in tRNA?
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Reply #1 on:
February 23, 2012, 10:06:12 AM »
It appears that is jargon for 5-methyluridine, which is another way of saying ribothymidine.
http://en.wikipedia.org/wiki/5-Methyluridine
I recognize that its a bit confusing sometimes, we're taught that thymidine pairs with adenine in DNA, uracil pairs for RNA. But living things use a variety of modified bases for specialized needs.
http://pubs.acs.org/doi/abs/10.1021/bi00456a016
We generally (but not always) reserve the term "methylation" for adenine and cytidine residues. Unless we're making cancer drugs.
http://en.wikipedia.org/wiki/DNA_methylation#In_mammals
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Hey, I'm not judging. I just like to shoot straight. I'm a man of science.
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What nucleotide is mU in tRNA?