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Topic: EX-527| CAS 49843-98-3 | sun-shinechem  (Read 3343 times)

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Offline sun-shine

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EX-527| CAS 49843-98-3 | sun-shinechem
« on: June 04, 2012, 08:49:22 PM »
EX-527;
CAS#49843-98-3;
Purity:98%;
in stock.
contact us:
www.sun-shinechem.com;
sales@sun-shinechem.com;


Biological Activity:

Selective inhibitor of SIRT1 that does not inhibit histone deacetylase (HDAC) or other sirtuin deacetylase family members (IC50 values are 98, 19600, 48700, > 100000 and > 100000 nM for SIRT1, SIRT2, SIRT3, HDAC and NADase respectively). Enhances p53 acetylation in response to DNA damaging agents.   

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