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Topic: what is the chemical equation and reaction for the hydrolysis of acetaminophen?  (Read 13822 times)

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Offline grangerfor222

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what is the chemical equation and reaction for the hydrolysis of acetaminophen?
« on: July 29, 2012, 05:12:59 AM »
i cant find it anywhere!
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Offline sjb

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Re: what is the chemical equation and reaction for the hydrolysis of acetaminophen?
« Reply #1 on: July 29, 2012, 05:20:44 AM »
Quote from: grangerfor222 on July 29, 2012, 05:12:59 AM
i cant find it anywhere!


What functional groups does acetaminophen have?
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Offline grangerfor222

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Re: what is the chemical equation and reaction for the hydrolysis of acetaminophen?
« Reply #2 on: July 29, 2012, 06:10:32 AM »
Quote from: sjb on July 29, 2012, 05:20:44 AM
Quote from: grangerfor222 on July 29, 2012, 05:12:59 AM
i cant find it anywhere!


What functional groups does acetaminophen have?
umm well it has an amide and hydroxyl functional group im pretty sure?
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Offline AWK

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Re: what is the chemical equation and reaction for the hydrolysis of acetaminophen?
« Reply #3 on: July 29, 2012, 06:14:19 AM »
Which of these two groups can undergo hydrolysis?

http://en.wikipedia.org/wiki/Paracetamol
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Offline grangerfor222

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Re: what is the chemical equation and reaction for the hydrolysis of acetaminophen?
« Reply #4 on: July 29, 2012, 06:36:06 AM »
hmmm not entirely sure. it says that hydrolyses with hcl but im not sure which of the functional groups it hydrolyses with?
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Offline AlphaScent

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Re: what is the chemical equation and reaction for the hydrolysis of acetaminophen?
« Reply #5 on: July 29, 2012, 10:51:46 AM »
What is the definition of hydrolysis?
What chemical elements are involved?

Once you know and understand those questions, work out the answer..

you need to show an attempt.

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Offline AWK

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Re: what is the chemical equation and reaction for the hydrolysis of acetaminophen?
« Reply #6 on: July 29, 2012, 12:12:07 PM »
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Offline grangerfor222

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Re: what is the chemical equation and reaction for the hydrolysis of acetaminophen?
« Reply #7 on: July 30, 2012, 04:18:02 AM »
ok so when paracetamol undergoes hydrolysis it goes back to form p-aminophenol (base?) and acetic anhydride (acid). is that right?
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Offline AWK

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Re: what is the chemical equation and reaction for the hydrolysis of acetaminophen?
« Reply #8 on: July 30, 2012, 04:38:09 AM »
Acetic anhydride is a derivative of acid - during hydrolysis acid and base a formed!
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Offline grangerfor222

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Re: what is the chemical equation and reaction for the hydrolysis of acetaminophen?
« Reply #9 on: July 31, 2012, 03:56:39 AM »
ooo ok so does that mean i was right with my above post? thank youu
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Offline AWK

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Re: what is the chemical equation and reaction for the hydrolysis of acetaminophen?
« Reply #10 on: July 31, 2012, 04:08:20 AM »
no - acetic anhydride is derivative of acid - not acid itself. Acetic anhydride cannot exist in the presence of water.
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Offline grangerfor222

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Re: what is the chemical equation and reaction for the hydrolysis of acetaminophen?
« Reply #11 on: August 01, 2012, 02:02:55 AM »
ahh ok. so when paracetamol hydrolysis it produces p-aminophenol? and then would it also produce acetic acid?
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Offline camptzak

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Re: what is the chemical equation and reaction for the hydrolysis of acetaminophen?
« Reply #12 on: August 03, 2012, 12:26:11 AM »
I think this might be helpful.

Hydrolysis. Hydro(water) Lyse (break)

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