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I've been looking at different software packages to aid in statistical modeling, design of experiments, and evaluating robustness of chromatographic methods.  So far, I've heard of Drylab from the Molnar Institute, Fusion AE from S-Matric, and Autochrom MDS from ACD Labs.  Does anyone here have experience with these or know of other similar software?  What were your experiences like and would you recommend a particular program?