[kohd]

Anyone know a detailed prep for the schiff base ligands of 2,6-diformyl-4-methylphenol and diamines? Most just say reflux in ethanol only this leads to insoluble and/or sticky side products. Thanks for any help

[ssrimurugan]

Hallo friend,

So what u get as a sticky material may actually be either a polymer or a macrocycle (insoluble in EtOH; but soluble in CH2Cl2, CHCl3...). This is a general way to synthesis these materials.

[movies]

I've made Schiff base, salen type ligands by the "refluxing ethanol" method before and it worked fine, but I was using aromatics with only one aldehyde.  That second aldehyde on your aromatic portion may be leading to polymerization, as suggested above.  I don't think that I encountered any gummy residue, the reaction was pretty clean.