Topic: Asymmetric synthesis of (S,S)-hydrobenzoin (Read 1540 times)

CHEKAL · « **on:** November 23, 2012, 05:23:13 PM »

How would I go about a synthesis for (S,S)-hydrobenzoin in enantiomeric excess?

I know asymmetric dihysroxylation with osmium tetroxide would work for synthesis but this gives a racemic product.

I need a synthesis that has S,S enantiomeric excess without resolution.

Thanks

discodermolide · « **Reply #1 on:** November 23, 2012, 08:52:29 PM »

Here is an Org. Syn prep of the (R)(R) enantiomer, perhaps the other catalyst isomer is available?
http://www.orgsyn.org/orgsyn/pdfs/v82p0010.pdf

Topic: Asymmetric synthesis of (S,S)-hydrobenzoin (Read 1540 times)

CHEKAL

Asymmetric synthesis of (S,S)-hydrobenzoin

discodermolide

Re: Asymmetric synthesis of (S,S)-hydrobenzoin

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