Topic: D2O (Read 4262 times)

kapital · « **on:** January 30, 2013, 10:54:22 AM »

I know when we add D2O basic and acid protons disappear from ¹H spectrum, due to change, but what happen when some peaks change their chemical shift, when a D2O is added to sample?

discodermolide · « **Reply #1 on:** January 30, 2013, 11:44:15 AM »

Perhaps you added too much, 1 drop is all you need.

kapital · « **Reply #2 on:** January 31, 2013, 02:03:45 AM »

No I did not mean practically, I meant theoretically. I saw some exercises, where it says peak change chemical shift after D2O is added.

discodermolide · « **Reply #3 on:** January 31, 2013, 02:17:22 AM »

Well if the NMR solvent is water miscible then I would expect a shift in the signal.

kapital · « **Reply #4 on:** January 31, 2013, 04:07:07 AM »

So the acid base peaks are only ones, besides solvent, that can change, when D2O is added to sample?

discodermolide · « **Reply #5 on:** January 31, 2013, 04:21:07 AM »

No. The shifts in methanol and methanol/ water will be slightly different

Topic: D2O (Read 4262 times)

kapital

D2O

discodermolide

Re: D2O

kapital

Re: D2O

discodermolide

Re: D2O

kapital

Re: D2O

discodermolide

Re: D2O

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