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Topic: acyl chloride reaction with amine  (Read 1317 times)

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Offline starxlit3

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acyl chloride reaction with amine
« on: March 16, 2013, 04:14:46 PM »
I'm having significant trouble with my reaction.

I am reacting L-carnosine with phenothiazine-10-carbonyl chloride, but am having significant trouble with this reaction.

L-carnosine is soluble in water, not even DMSO! But phenothiazine-10-carbonyl chloride is more non-polar, and is soluble in DCM, but not water. I'm having trouble finding a solvent that will dissolve both to allow them to react.

help please :(

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