[pollypui]

anyone know the pKa of pyroglutamaic acid with reference~
thank you very much!!

[Arkcon]

Plenty of people do:  http://lmgtfy.com/?q=pyroglutamaic+acid  You could find it at the Wikipedia article, or on the vendor MSDS, for example, Sigma-Aldrich

[pollypui]

Plenty of people do:  http://lmgtfy.com/?q=pyroglutamaic+acid  You could find it at the Wikipedia article, or on the vendor MSDS, for example, Sigma-Aldrich

i try it before many time, but i cant found it out:'(

[Arkcon]

The first and third results in my Google search, which I linked to above, contained the information you need.

[pollypui]

The first and third results in my Google search, which I linked to above, contained the information you need.

The first one is wiki, the reference article that i cant find the free version.
this is my final year project, so i must find it out prove my data right~
and the pka of pyroglutamic acid do not show in the sigma MSDS....

[AWK]

The first pK

a

(-1.76) is Wikipedia is suspicious

[pollypui]

The first pK

a

(-1.76) is Wikipedia is suspicious

yes.. so i need the pka with the reference, and i find many hand book.
and none of book have the pKa of pyroglutamaic acid
anyone can help me ><

[billnotgatez]

Is the information on
http://www.hmdb.ca/metabolites/hmdb00267
relevant

that was the 7th GOOGLE item

[Arkcon]

The first one is wiki, the reference article that i cant find the free version.
this is my final year project, so i must find it out prove my data right~
and the pka of pyroglutamic acid do not show in the sigma MSDS....

Sorry.  But this is silly.  If wikipedia isn't a useful reference for you, how is a forum posting acceptable?  Will your bibliography or footnote list: personal communication, The Cheimestrie Geeks forums, user: Pee-Kay-Hay God ?  That's not a good reference either.  You will simply have to search the library for a decent source, or buy one.

[AWK]

http://link.springer.com/article/10.1007%2Fs10953-005-5121-x?LI=true

Journal of Solution Chemistry
July 2005, Volume 34, Issue 7, pp 853-867

Electrical Conductance and Volumetric Studies in Aqueous Solutions of DL-Pyroglutamic Acid
Zoya Orekhova, Yonit Sambira, Emanuel Manzurola, Alexander Apelblat

[pollypui]

The first one is wiki, the reference article that i cant find the free version.
this is my final year project, so i must find it out prove my data right~
and the pka of pyroglutamic acid do not show in the sigma MSDS....

Sorry.  But this is silly.  If wikipedia isn't a useful reference for you, how is a forum posting acceptable?  Will your bibliography or footnote list: personal communication, The Cheimestrie Geeks forums, user: Pee-Kay-Hay God ?  That's not a good reference either.  You will simply have to search the library for a decent source, or buy one.

sorry to my impolite..

[AWK]

In my reference pK_a1 of pyroglutamic acid was measured. Moreover, references to previous measurements are given.

[Corribus]

If you're having so much trouble finding this value, why not just measure it yourself?

[pollypui]

In my reference pK_a1 of pyroglutamic acid was measured. Moreover, references to previous measurements are given.

thank you very much!!
is that mean PCA only have one pka?

[AWK]

Just look at structural formula