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Topic: Aminoacyl-tRNA  (Read 2622 times)

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Offline opel65

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Aminoacyl-tRNA
« on: May 24, 2013, 08:51:50 AM »
My question is if this tRNA needs ATP for its sythesis? In my biochemistry book it says that aminoacyl-tRNA synthetase recognizes an amino acid and its cognate aminoacyl tRNA catalyzing their covalent attachment. The reaction requires ATP which is cleaved to AMP.

So ATP is used in joining amino acids with its tRNA, NOT for synthesis of aminoacyl-tRNA right? Cause the aminoacyl-tRNA(the enzyme) binds existing aminoacyl-tRNA to the amino acid?

Sorry if this is confusing, anyone has a take on this?

Offline Babcock_Hall

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Re: Aminoacyl-tRNA
« Reply #1 on: May 24, 2013, 09:06:23 AM »
When you join an amino acid to a tRNA, the product is called an aminoacyl tRNA.  The enzyme that does this is called an aminoacyl tRNA synthetase, and it does indeed use ATP as its third substrate.

Offline opel65

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Re: Aminoacyl-tRNA
« Reply #2 on: May 24, 2013, 09:11:29 AM »
Ah thank you, ofcourse how could I not see it.

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