November 28, 2024, 02:44:06 AM
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Topic: Sidechain Cleavers  (Read 2173 times)

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Offline johndohnal

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Sidechain Cleavers
« on: October 28, 2013, 01:17:33 PM »
Are there any known enzymes which cleave the sidechains (not backbones) of lysine or arginine?  Smaller enzymes would be better.  If no known enzymes which cleave lysine or arginine, then any enzymes which cleave the sidechains of any amino acids would be appreciated.

Thanks,
John

Offline Babcock_Hall

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Re: Sidechain Cleavers
« Reply #1 on: October 28, 2013, 05:27:10 PM »
It is difficult even to envision how one would remove a side chain ammonium ion (lysine).  I don't know of any enzymes that act on these two side chains, but there are chemical reagents which react with one or the other side chain.

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