October 31, 2024, 09:28:26 PM
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Topic: Optimizing reaction conditions: temperature, pH, etc.  (Read 1673 times)

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Offline ajohnson388

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Optimizing reaction conditions: temperature, pH, etc.
« on: March 30, 2014, 05:40:05 PM »
Hi,

I am about to finish my second semester of organic chemistry, but have still yet to learn how to derive reactions conditions for syntheses. I was wondering if anyone can lead me in the right direction, via books, links, or keywords, so i can learn more on how to derive the best pH, temperature, and pressure values for any synthesis. Surprisingly, I am having a great deal of trouble finding this information, so any pointers would be great. Also, I am not looking for qualitative information such as heat or no heat, but actual values that can be predicted or close to it.

Thanks,
Andrew

Offline discodermolide

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Re: Optimizing reaction conditions: temperature, pH, etc.
« Reply #1 on: March 30, 2014, 09:13:17 PM »
No hard and fast rules, just lots of experience. Also lots of literature experimental procedures one can follow.
Chemistry is an experimental science.
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Offline orgopete

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Re: Optimizing reaction conditions: temperature, pH, etc.
« Reply #2 on: March 31, 2014, 10:12:21 AM »
I agree with Disco. One of my favorite places to start is with Organic Synthesis. It is very useful to read the notes here as well.
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