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Topic: Major side product of Suzuki coupling involving sterically hindered boronic acid  (Read 3392 times)

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Offline kamiyu

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Major side product of Suzuki coupling involving sterically hindered boronic acid
« on: July 10, 2014, 01:56:15 PM »
Recently doing coupling using 2,4,6-trimethylphenylboronic acid. Found to be sluggish and quite a lot of starting material found.

Any suggestion how to improve the yield??? what is the main side reaction???
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Offline Mitch

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Re: Major side product of Suzuki coupling involving sterically hindered boronic acid
« Reply #1 on: July 10, 2014, 03:23:17 PM »
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