[corax23]

Hello!!

I need help for this synthesis:  

Thanks!

[AromaticAcrobatic]

How far have you gotten? What's confusing you?

 

[orgopete]

How many more carbons do you need to add? What might be a good source?

[corax23]

I did it!! I can create a ketone with the reagent and H₂O and I added the ketone to the acetylide.

[kriggy]

Indeed. YOu probably need to reduce the triple bond

[Altered State]

I did it!! I can create a ketone with the reagent and H₂O and I added the ketone to the acetylide.

Just some comments on that:

You can perfectly generate acetone from that alkyne, but actually, you wouldn't have to "create" a ketone, the one you need is just acetone, CH₃C(=O)CH₃, using propyne to make acetone would be a waste of time and money. But if you are asked to use that reagent as your only carbon source, is fine.

Also, then, mechanistically speaking, you add the acetylide to the ketone, not the other way around.