[Altered State]

Here is this week's target, rules can be found here. http://www.chemicalforums.com/index.php?topic=77867.msg284036#msg284036

Here is this week problem:





Maybe too many stereocenters?
Well, I propose something like this because I want to improve my knowledge about stereochemistry control, an seeing examples is one of the best ways to do so, but feel free to propose non-stereoselective approaches too, I'll probably do one myself.

[critzz]

Wow, nice molecule, lots of functional groups (does it even exist? ^^).
I always like challenges, so here is my asymmetric synthesis proposal:

[kriggy]

We have almost exactly the same path to make the heterocyclic part. I´ll post my way later today (It lacks some stereochemistry control :/ )

[kriggy]

It looks like its dying a bit..
Sorry, it took me bit longer than I expected.. Not much stereochemistry control on my part, im seriously lacking in the area.

]

The 1st equivalent of grignard is to neutralize the COOH group. Im thinking that some stereochem control could be implemented but yea.. not today