I'm trying to reduce the methyl ester of a diterpene, but a I have not success.
NaBH4/I2And I 'm using this system. Someone has used ?
I have a flask ester solution in THF ,
I have another flask a solution of NaBH4 in THF
And I have another flask a solution of iodine in THF.
Then I added the ester solution to the solution of NaBH4 , after 10 minutes, add the iodine solution .
The article mentions that owe iodine added in 30 minutes but it added in 10 minutes , it affects ?
My tetrahydrofuran is impure also , I put on a TLC plate eluting off a compound .
Could anyone help me?