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Topic: the limitation of friedel craft alkylation?  (Read 4548 times)

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bisser

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the limitation of friedel craft alkylation?
« on: April 17, 2006, 08:13:51 PM »
is friedel craft alkylation not applicable to aromatic amine?
« Last Edit: April 17, 2006, 11:14:33 PM by bisser »
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saltyf

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Re: the limitation of friedel craft alkylation?
« Reply #1 on: May 19, 2006, 03:50:12 AM »
you should protect the amine first
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Offline Donaldson Tan

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Re: the limitation of friedel craft alkylation?
« Reply #2 on: May 20, 2006, 09:50:24 PM »
I don't think you want the amine group to attack the reactive intermediate of the Friedel Craft Alkylation.
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