Hello,
so I am not very great at chemistry, but I have a homework from organic chemistry, that I don't know how to complete. I would be very happy for your help. Thanks in advance
So the task goes:
1-Benzylpiperidone reacts with chloro(4-chlorophenyl)magnesium, product of this (A) reaction is debezyled (B). B then reacts with 4-Bromo-N,N-dimethyl-2,2-diphenylbutanamide (+Na
2CO
3)
+
A
A
B (debenzylation)
B +
C
So now what I've got: I think that A will be 1-Benzyl-4-phenyl-4-piperidinol (I don't think, I can make this one using SMILES, sorry), since grignard reagent should react this way with ketones..
Then B, I have no idea. I failed to find more information or debenzylation (or I found things like this:
https://www.researchgate.net/figure/223613177_fig1_Fig-1-Debenzylation-reaction-structural-variability-of-substrate-and-protecting-group it describes functional groups, but none of them is same as in my case.)
Then (from the task) I know that C is medicine of some sort, but without B, I can't really continue.
I will be thankful for any help