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Topic: Can anybody help me doing this exercise?  (Read 2389 times)

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Offline guzmanov

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Can anybody help me doing this exercise?
« on: May 27, 2017, 12:43:41 PM »
I know is a Claisen condensation but i'm not sure how to do the mechanism nor what happens after you add H2O. :(

Thank you in advance! :D

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Offline sjb

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Re: Can anybody help me doing this exercise?
« Reply #1 on: May 27, 2017, 01:20:39 PM »
What happens if you just try a Claisen addition (looking at the number of oxygens)?
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Offline kriggy

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Re: Can anybody help me doing this exercise?
« Reply #2 on: May 27, 2017, 02:06:48 PM »
Quote from: guzmanov on May 27, 2017, 12:43:41 PM
I know is a Claisen condensation ...

its not Claisen however
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Offline spirochete

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Re: Can anybody help me doing this exercise?
« Reply #3 on: June 05, 2017, 02:53:12 PM »
First few steps look like aldol or Knoevenagal (sp?). Second set of steps look like key steps from malonic ester/acetoacetic ester synthesis.

-H2O means "loss of water" by the way. It does not mean "add water". In case that was a point of confusion.
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