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Aspirin synthesis reaction???
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Topic: Aspirin synthesis reaction??? (Read 4582 times)
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1forest1
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Aspirin synthesis reaction???
«
on:
October 19, 2017, 01:45:20 PM »
Is the reaction for the synthesis of aspirin with salicylic acid and acetic anhydride a reversible reaction?? could equilibrium be used to explain why the percentage yield is low??
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Arkcon
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Re: Aspirin synthesis reaction???
«
Reply #1 on:
October 19, 2017, 02:14:32 PM »
Start by writing the reaction out. See if something about the products or reactants makes a reverse reaction unlikely.
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Hey, I'm not judging. I just like to shoot straight. I'm a man of science.
1forest1
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Re: Aspirin synthesis reaction???
«
Reply #2 on:
October 19, 2017, 02:18:04 PM »
im not quite sure what you mean. I know the the reactants are salicylic acid and acetic anhydride and the products formed are aspirin and acetic acid. But isn't that an esterification reaction?? and I thought those were reversible
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Arkcon
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Re: Aspirin synthesis reaction???
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Reply #3 on:
October 19, 2017, 04:09:59 PM »
This reaction?:
https://en.wikipedia.org/wiki/Aspirin#Synthesis
No, its not reversible.
https://en.wikipedia.org/wiki/Ester#Alcoholysis_of_acyl_chlorides_and_acid_anhydrides
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Hey, I'm not judging. I just like to shoot straight. I'm a man of science.
1forest1
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Re: Aspirin synthesis reaction???
«
Reply #4 on:
October 19, 2017, 04:39:20 PM »
thanks, just got myself a bit confused
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Aspirin synthesis reaction???