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Equivalence salts
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Topic: Equivalence salts (Read 2155 times)
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minsc458
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Equivalence salts
«
on:
July 14, 2018, 07:13:02 AM »
Hello, do you know the equivalence of the differents salts of this molecule :
10 mg Tranylcypromine sulfate Molecular Weight : 364.46 g/mol
10 mg Tranylcypromine hydrochloride Molecular weight :169.65 g/mol
10 mg Tranylcypromine hydrochloride will have 2.14 times more tranylcypromine than 10 mg Tranylcypromine sulfate.
Is it correct?
Thanks for your help
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billnotgatez
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Re: Equivalence salts
«
Reply #1 on:
July 14, 2018, 05:13:32 PM »
Can we assume the following
considering there are many results from searching
From PubChem
Tranylcypromine sulfate
MW: 364.460 g/mol
MF: C
18
H
24
N
2
O
4
S
Tranylcypromine hydrochloride
MW: 169.652 g/mol
MF: C
9
H
12
ClN
Tranylcypromine
MW: 133.194 g/mol
MF: C
9
H
11
N
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minsc458
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Re: Equivalence salts
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Reply #2 on:
July 14, 2018, 05:30:30 PM »
Yes it's the first two results.
the difference in molecular weight means 10 mg of the sulfate form is two times less potent than 10 mg of the hydrochloride form ?
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wildfyr
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Re: Equivalence salts
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Reply #3 on:
July 14, 2018, 05:48:39 PM »
No, they are about the same. The sulfate has two transylamines to one sulfate, but the hydrochloride is 1 amine to each chloride. It's because sulfate is a divalent anion, and chloride is monovalent.
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minsc458
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Re: Equivalence salts
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Reply #4 on:
July 14, 2018, 05:58:16 PM »
ok thanks for the explanation.
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Equivalence salts