Topic: Ortho-Para director question. (Read 1502 times)

JoeyBob · « **on:** March 16, 2020, 08:57:36 PM »

If you have an activating substituent that's an ortho-para director, how do you determine if the ortho product is the major product or if the para product is the major product?

chenbeier · « **Reply #1 on:** March 17, 2020, 05:03:39 AM »

Not easy, depend which groups already existing.

Babcock_Hall · « **Reply #2 on:** March 17, 2020, 11:16:06 AM »

What factor or factors do you think might come into play?

JoeyBob · « **Reply #3 on:** March 17, 2020, 04:03:54 PM »

Quote from: Babcock_Hall on March 17, 2020, 11:16:06 AM

What factor or factors do you think might come into play?

Steric hindrance? So the Para is the primary product?

Babcock_Hall · « **Reply #4 on:** March 18, 2020, 04:26:50 PM »

I suspect that it depends on the size of the group, but yes, that was what I was thinking as well.

Topic: Ortho-Para director question. (Read 1502 times)

JoeyBob

Ortho-Para director question.

chenbeier

Re: Ortho-Para director question.

Babcock_Hall

Re: Ortho-Para director question.

JoeyBob

Re: Ortho-Para director question.

Babcock_Hall

Re: Ortho-Para director question.

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