December 22, 2024, 04:55:19 PM
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Topic: Organic chemistry  (Read 1085 times)

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Offline kjyotishman48

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Organic chemistry
« on: September 20, 2020, 02:19:57 AM »
Please help me to write the reaction mechanism of the following reaction (attached in the picture below)

Offline sjb

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Offline Enthalpy

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Re: Organic chemistry
« Reply #2 on: September 21, 2020, 04:40:12 PM »
Interesting! Is the ketone necessary to the reaction? Two more carbons and a small spiro would inject fuss into banal compounds to serve as, well, you know.
carene CC2(C)C1CC=C(C)CC12
alpha-Pinene C1=C(C2CC(C1)C2(C)C)C
beta-Pinene C1(=C)C2CC(CC1)C2(C)C

Can sodium amide be prepared in small amount at the last moment next to the main reactor? By recycling NH3 and electrolysing molten NaBr?
Or is lithium amide advantageous?

Offline Enthalpy

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Re: Organic chemistry
« Reply #3 on: September 23, 2020, 03:54:51 PM »
Any link? A reaction name maybe?

What I've seen up to now is that sodium amide abstracts HX very efficiently and can close cycles. I guess it rips two H from the other molecule in the OP reactions.

But this doesn't tell me whether a ketone group is needed.

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