December 26, 2024, 10:57:14 PM
Forum Rules: Read This Before Posting


Topic: Major product of 2-iodopropane + sodium ethoxide  (Read 3831 times)

0 Members and 1 Guest are viewing this topic.

Offline Meter

  • Full Member
  • ****
  • Posts: 268
  • Mole Snacks: +14/-5
  • Take what I say with a grain of salt
Re: Major product of 2-iodopropane + sodium ethoxide
« Reply #15 on: November 25, 2020, 05:58:02 PM »
You have a secondary alkyl iodide, not a tertiary.  The reading I have done indicates that if one uses a polar, aprotic solvent, one might tilt things toward the SN2.  Can you give an example of such a solvent?
Yes, I'm aware that it's not tertiary. It was just a point where SN2/E2 are clear differentiated.

Acetone is one such solvent right? If I understand correctly, aprotic means that it has no O-H bonds (like water and all alcohols). Simple ketones generally don't have such bonds since the oxygen bonds to carbon only.


Offline Babcock_Hall

  • Chemist
  • Sr. Member
  • *
  • Posts: 5715
  • Mole Snacks: +331/-24
Re: Major product of 2-iodopropane + sodium ethoxide
« Reply #16 on: November 26, 2020, 04:45:32 PM »
Yes, you are correct about acetone.  DMF and DMSO are two other polar, aprotic solvents.

Sponsored Links