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Topic: Oxycodone synthesis  (Read 2018 times)

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Offline Zeon37

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Oxycodone synthesis
« on: January 22, 2021, 07:44:38 PM »
Hi everyone! For one of my chem assignments we have to take a compound and write out the synthesis in detail and explain verbally a breakdown of each step.
I chose one of the semi-synthetic opioids—oxycodone—. I’m really confused on what to do following hydrogenation. It’s says to wash with water and dry over sodium sulfate in vacuo. Please help me!!
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Offline Borek

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Re: Oxycodone synthesis
« Reply #1 on: January 23, 2021, 04:06:38 AM »
Quote from: Zeon37 on January 22, 2021, 07:44:38 PM
write out the synthesis in detail

I am afraid discussing practicalities of the synthesis will be against our forum rules. No problems with discussing reaction mechanism though.
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Offline AWK

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Re: Oxycodone synthesis
« Reply #2 on: January 23, 2021, 05:34:32 AM »
You must read this publication and the relevant publications cited in it carefully.
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