[RH111]

Hi,

From what I understand, for a Carbon atom to be a stereogenic center, it needs to be bonded to 4 distinct groups.  I was wondering whether two stereoisomers (of the E and Z configurations) would be considered distinct groups and make the compound chiral; or if they are considered identical and thus make the compound achiral.

Thanks!

[Borek]

I was wondering whether two stereoisomers (of the E and Z configurations) would be considered distinct

Yes.

[RH111]

Thanks for your response. In that case how would I assign priority to those groups (the E-Z stereoisomers) to determine the R-S configuration of the molecule?

~RH111

[Borek]

Come on, have you even tried?

https://en.wikipedia.org/wiki/Cahn–Ingold–Prelog_priority_rules#Geometric_isomers