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Topic: Testing for superiority between two versions of PEGylated IFN  (Read 3144 times)

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Offline edgardoodle

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Testing for superiority between two versions of PEGylated IFN
« on: December 11, 2021, 08:33:25 PM »
Hello,

I need to have two Pegylated Interferons tested for quality to determine which sample is superior. The only difference in the two versions are the raw pegylation materials used.

Which specific lab tests would you recommend?

Thank you!
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Offline Borek

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Re: Testing for superiority between two versions of PEGylated IFN
« Reply #1 on: December 12, 2021, 03:41:09 AM »
Doesn't it depend on how you define "superior" for your needs?
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Offline edgardoodle

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Re: Testing for superiority between two versions of PEGylated IFN
« Reply #2 on: December 12, 2021, 07:55:22 PM »
"Superior" would be based mostly on potency, antiviral activity. Also, purity, bioavailability, overall quality and safety, protein activity.

 
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Offline jeffmoonchop

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Re: Testing for superiority between two versions of PEGylated IFN
« Reply #3 on: December 13, 2021, 11:55:46 AM »
Depends if you have in vitro or in vivo capabilities.
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