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Topic: Magnesium bisglycinate + citric acid = ?  (Read 1573 times)

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Offline ivan.novak

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Magnesium bisglycinate + citric acid = ?
« on: May 05, 2023, 09:55:13 AM »
Hello,
I have a question or two that I need help with:
What happens when you put magnesium bisglycinate and citric acid into water solution?
Does magnesium change form here?

Kind regards,
IN

Offline Borek

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Re: Magnesium bisglycinate + citric acid = ?
« Reply #1 on: May 06, 2023, 03:16:46 AM »
Two processes I can think of that could change the composition of the solution are protonation of glycine and production of iron citrate complex. Hard to tell what will happen without checking exact equilibrium constants.
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Offline ivan.novak

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Re: Magnesium bisglycinate + citric acid = ?
« Reply #2 on: May 09, 2023, 02:30:45 AM »
Hi, maybe it could help if I gave you more details on the solution composition:
I used 3848mg of magnesium bisglycinate and 3650 mg of citric acid to prepare the solution.
BR,
IN

Offline Hunter2

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Re: Magnesium bisglycinate + citric acid = ?
« Reply #3 on: May 09, 2023, 05:13:42 AM »
Magnesium doesnt change. It stays as how it is as Mg2+.

Offline Borek

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Re: Magnesium bisglycinate + citric acid = ?
« Reply #4 on: May 09, 2023, 11:43:28 AM »
Magnesium doesnt change. It stays as how it is as Mg2+.

No, it is present not as Mg2+ but as bisglycinate complex, which - depending on the pH, concentrations and stability constants - can be to some extent converted into citrate complex. Each form has different bioavailability.

Finding exact equilibrium would require browsing databases in hunt for data.
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Offline Hunter2

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Re: Magnesium bisglycinate + citric acid = ?
« Reply #5 on: May 09, 2023, 12:43:17 PM »
In both complexes, glycinate and citrate is Magnesium still 2+ charged. Maybe it has a higher coordination number. 6 I guess .

Offline Borek

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Re: Magnesium bisglycinate + citric acid = ?
« Reply #6 on: May 11, 2023, 09:49:11 AM »
Depends on how you understand "magnesium form". While at the core there is the same cation, from the biological and dietary pov these are completely different compounds and completely different forms.
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