Adjust the order of mixing: Instead of adding HEC directly to the mixture, try adding it gradually while stirring continuously. Start by mixing the Finasterid, propylene glycol, and ethanol together until well combined. Then, slowly sprinkle the HEC into the mixture while stirring vigorously. This method can help prevent clumps from forming.
Pre-hydrate the HEC: Another approach is to pre-hydrate the HEC before adding it to the mixture. Dissolve the HEC in a separate container of water, ensuring that it absorbs and disperses fully. Once the HEC has formed a gel-like consistency, you can gradually add it to the mixture while stirring continuously.
Increase agitation time: If the above methods still result in clumps, try increasing the duration and intensity of the stirring or mixing process. This can help break down the clumps and promote better dispersion of the HEC.
Use a different solvent: If all else fails, consider using a different solvent or combination of solvents that may be more compatible with HEC. You can experiment with alternative solvents such as glycerin or polyethylene glycol (PEG), which are known to have good solubility with HEC.