[Maui3]

I do amatuer chemistry. Could anyone please help me on a procedure to extract apiole from parsley oil? Wikipedia says "In 1715, the Leipzig pharmacist Heinrich Christoph Link discovered apiol during the steam distillation of parsley oil." and "Heinrich Christoph Link, an apothecary in Leipzig, discovered the substance in 1715 as greenish crystals reduced by steam from oil of parsley.". I assume" reduced by steam" means steam distillation, but I don't really see where in the process of steam distillation of parsley oil (which has already been steam distilled from parsley) will crystallize out apiole..

I am very confused. Some guidance would be appreciated.

[Maui3]

I should probably add (because of its traditional uses) that I won't use it as an abortifacient..

[rolnor]

You have a reference in the wikipedia, have you checked it? I would use chromatography on silica gel or vacuum distillation, its fairly volatile.
Here is the reference:

https://en.wikipedia.org/wiki/Apiole#cite_ref-2

[Maui3]

Thank you. But those aren't really options for me in my amatuer lab. Also.. Apiole is a solid at room temp. so would it be possible to exploit that to isolate it?

[rolnor]

Its melting point is 30 Celsius.
You need some equipment to isolate this, a silica gel column is not difficult to fix. Look at ebay. Then you need some silica and solvent, these are not impossible to obtain. Vacuum distillation is also not impossible, you need a vacuum pump, ebay again.

https://www.ebay.com/itm/204801107257?_nkw=distillation&itmmeta=01J76D6R7TMZVCW7THBBKF0QDN&hash=item2faf18e539:g:M2AAAOSwfYFmTu1R&itmprp=enc%3AAQAJAAAA8HoV3kP08IDx%2BKZ9MfhVJKmn%2BhbSBmJls01gDwqLiZzB6pAVUPNRjxufd50IkJx5z%2BBCCmEqt3eQO28fJGYb7Vn1lbbGdaAGHrZyiIFHPysxf00Zl750%2F4Uig5RLuTYUHeydGVZ1bSYS0AEqPxV0fGYBGu6xAsc80EZ%2FcamfJzljei0ZIj%2BBdr%2FakSJe2OnWDdF%2Fh4i8%2B9zeyOlOtb46QYJpGNkUDmDFmloRpbd8XmtuiIEewQip5u4nRfg6poCwQVTTGq0SOsD3KgS%2FDOED1dDL7mbidD1oEMJAIXXZe%2B3SehqW%2BsWFMogCYRpnEsBW9Q%3D%3D%7Ctkp%3ABFBMkoSbzblk

https://www.ebay.com/itm/394378474796?_nkw=vacuum+pump&itmmeta=01J76DBMPYJYEDGMYP7MBFS7N9&hash=item5bd2c9f52c:g:l1sAAOSw~yNjmX-p&itmprp=enc%3AAQAJAAAA8HoV3kP08IDx%2BKZ9MfhVJKlQvKcg8BQsYi9X65zZ1gV31qkjyGLLNoiX4%2BAztT%2BvXFahi%2B%2FhUNPYP6beZIymdOAqVlOqYA8JaDeg83Lytt%2FdZ90ih%2BTwdKQD6cbiOC%2BfF3YIKHWTuj3VuUkd4KkuE%2FUw2%2FlxSlxPtptHyx%2F2AQ6FRYVunZYgTb4YbQw8PTfTG1H2fUTEE9iXBQo2DmB%2B%2FTpHhsb4GI8faAj5lT9xQpmm1pwbghMO1PV0WkXtFX93qYOYeWR5YhdvHAoE0BVi5Jhbh16HJReJqJ3Gszq3eKqbmHQkd6TYZQ7uWtFWjoMcIg%3D%3D%7Ctkp%3ABk9SR4rMrs25ZA

https://www.ebay.com/itm/326087551644?_nkw=cromatogpraphy+column&itmmeta=01J76DDXC14E5H9X54A7GPMNC1&hash=item4bec552a9c:g:DvoAAOSwR45mGZVD&itmprp=enc%3AAQAJAAAA0HoV3kP08IDx%2BKZ9MfhVJKnM5r0iq%2BgekUcwL%2F5WQZxEPdXPd54pZZG5n%2FFZlJZQ%2FNNrbGm%2FpFhYpenJ7A8ndNW%2B%2B13nKSqh5SwjhSy6o%2F52Jp4eaX8jsQRFkXTLwUQoMVlFE7qyUGBv1Iotn8KNIEX%2FBqjrDyZkbge%2FE%2FHI1dYnTpjQ1RK7GW4XwIPjRkqM0oZB0tZVYBIc%2FUBqhmpwefjFsDdy97cbqW3u0wIE8FGytrIjdtBLvf%2F5pjuOSnZD0PNzJsVERqvUiFdLgdjnQkk%3D%7Ctkp%3ABk9SR5DWt825ZA

https://www.ebay.com/itm/387087711870?_nkw=silica+gel+for+chromatography&itmmeta=01J76DGD86SSWMNAHNMAXGD4TR&hash=item5a2039be7e:g:vI0AAOSwo4VmbUwb&itmprp=enc%3AAQAJAAAA4HoV3kP08IDx%2BKZ9MfhVJKkopaEPRvFTE%2Flf2Uk8NNGC%2BgYFyVwSNscl18BQMY38nINnOtzHRq0tQjuZxQWGFO0OTX0UmnG8%2FgfXeM6x4Ku8vQkuU%2Bzc6TCRYQpIYH%2FqIf2cRz70csaWzPS2MNJNHkSJBny64s2xI4eOAGpvj9GTbe5%2FP3%2FhEDBIm%2B1pQlRY1QCF5NqvS3R25qbhTSdubWJNvsmn2ME9jUZTrRG%2BP4RncWBCeSWtwvrzAbcxMt5%2BQ25U2nMJvqsSewMV%2Bw%2BOaghaa7f3za3r42Exnck4hWbR%7Ctkp%3ABk9SR5jUwc25ZA

solvents

https://www.amazon.de/-/en/generisch-Hexane-Petroleum-Fraction-Isomer/dp/B0CXNDHJLJ/ref=sr_1_2?crid=1BU3T6V17MLK0&dib=eyJ2IjoiMSJ9.mFvZ6A7E2x9cNe9YtsGtLSc7mDMzsUOGyqR3y7bf9wxozFhyLRLLtNzj8tkboFBvy0GQhP7_cHlk-6aBkm0wO8tJJ1K6j_Kq5z9_FrM2FxjHaIIVZFMUe2AlAiv3fX6Hmv5v1OL1pkivZDJnj7m9nQpm6b-mmth0VbYKIkfOAcdN25j9ELnl7JUgHub-s0VsfRVh7oB1eEU1X-AeNotjGDmfAKMxXp4a_8M2md1NsAHnGouFrO28shtBGkGmy1XpPbZNBMv5Kpf9tJoAikeAYZvUT-2zgwY1R6iO7sQFjqE.NXGKUcH2V7jJrpVGu4RvQ-ta9IwwxUpzWPUiOlsdXL8&dib_tag=se&keywords=hexane&qid=1725718689&sprefix=hexane%2Caps%2C152&sr=8-2

https://www.amazon.de/-/en/generisch-Ethyl-Acetate-Solvent-Colourless/dp/B0CXN9JPXW/ref=sr_1_7?crid=2EAV050YRO85N&dib=eyJ2IjoiMSJ9.FA2WMZQjpANeUrbj_kYgi9npqQUgXLxxtgw0NYgFh0wOBM_p9lOxiLLuRqTVs5RdGnbuVNyZOl8ZEUenVjd03axU6k9ThLB6i02noOXoDSGzErqZ6FaKFhenwao466O-p61uoiioenKA-VSyLoiR_bYW9X0Oz9P5bmWu18ogPMUH04ng16dV3B8gXO7pGOI3xqj16z7sGo4imOSSL6BbBkKLkEZE9lOLP1IkTa2KTShRV7BlY6w_zOzC4agm64XxeewCRMZ_2Sk-6UzxE9ifjNM0_epqBw8lseDMxyyVOzE.VI7zllUmJkPdDmtlfqSD_ogLEsO6KihytRPiMRKfYJA&dib_tag=se&keywords=ethyl+acetate&qid=1725718794&sprefix=ethyl+acetate%2Caps%2C144&sr=8-7