[TheBox]

''What is the role of dopamine? Dopamine acts on areas of the brain to give you feelings of pleasure, satisfaction and motivation. Dopamine also has a role to play in controlling memory, mood, sleep, learning, concentration, movement and other body functions.''


I hear the term Dopamine quite a lot when I am talking about MH and Psychology . Is Dopamine something of independent and distinct existence that can be detected under a microscope via blood samples or other , or is Dopamine actually unsupported Bio-Chem ?

[Babcock_Hall]

A microscope is not a way to detect dopamine or any other chemical.  Chemicals in the blood are typically detected via liquid chromatography-mass spectrometry or gas chromatography-mass spectrometry after suitable clean up.

[TheBox]

A microscope is not a way to detect dopamine or any other chemical.  Chemicals in the blood are typically detected via liquid chromatography-mass spectrometry or gas chromatography-mass spectrometry after suitable clean up.

We will take that as a no answer then , you can't detect Dopamine therefore Dopamine is speculation . By the way , my physics says feeling good or bad is a perception based on bio-electrics . Nothing to do with chemistry ! You can prove me wrong by providing a picture of the ''chemical'' Dopamine of course .

[Borek]

We will take that as a no answer then , you can't detect Dopamine therefore Dopamine is speculation

You can't observe dopamine with a microscope (using a tunneling microscope in very low temperatures it should be definitely possible though, but that's highly impractical), but sure you can detect it.

Same can be said about - say - electrons or magnetic fields, so by your logic they don't exist as well.

Dopamine is a compound with a well known properties, one that we know how to synthesize, how to separate, one that you can buy (as a hydrochloride) salt, one that is used intravenously as a medication in some cases. You really think it is all speculation?

You can prove me wrong by providing a picture of the ''chemical'' Dopamine of course .

Sure thing, image attached.

[Babcock_Hall]

https://pubchem.ncbi.nlm.nih.gov/compound/Dopamine
https://pubmed.ncbi.nlm.nih.gov/?term=dopamine+receptor&filter=simsearch2.ffrft&filter=pubt.review
The first link gives its properties.  The second link is a search of biomedical journal articles on the term "dopamine receptor."  I applied two filters, one specifying reviews and the other specifying that the paper must be available free of charge. There are about 2500 articles, which means that if I were researching the topic, I would probably want to apply additional filters.

[TheBox]

We will take that as a no answer then , you can't detect Dopamine therefore Dopamine is speculation

You can't observe dopamine with a microscope (using a tunneling microscope in very low temperatures it should be definitely possible though, but that's highly impractical), but sure you can detect it.

Same can be said about - say - electrons or magnetic fields, so by your logic they don't exist as well.

Dopamine is a compound with a well known properties, one that we know how to synthesize, how to separate, one that you can buy (as a hydrochloride) salt, one that is used intravenously as a medication in some cases. You really think it is all speculation?

You can prove me wrong by providing a picture of the ''chemical'' Dopamine of course .

Sure thing, image attached.

I am not being awkward or an ''enemy''of chemistry . My learning style is an absolute learing style , something Honey and Mumford never considered .

You say we can detect Dopamine , by this do you mean you can take a swab and it will show up on a machine test similar to an airport test machine or do you mean something else?

We don't actually detect electrons fyi , there is no way to test the elementary conserved charge of a particle . It is not like we can just attach an electrical test meter and measure a voltage etc . We can zoom in using special equipment and see latices etc but we cannot see the exact makeup of an atom. Protons , nuetrons and electrons are just one model we use that is accepted at this time but it isn't absolute either .
I recall some chemistry , the p-layers , but this is incorrect because it is not how the physics works .

If I ingest any chemical substance , we could take bloods or urine samples and the substance will show up in a toxicology report .

So you claim we can detect Dopamines, I disagree unless you are using brain fluid or other ,then analising this  .

I'll be blunt , you are saying to me , you know what is in an unlabelled can without opening it .

Could you please explain the method of detection for me ?

I want to believe you but I require absolute proofs , not something that only exists written on paper .


 

[TheBox]

https://pubchem.ncbi.nlm.nih.gov/compound/Dopamine
https://pubmed.ncbi.nlm.nih.gov/?term=dopamine+receptor&filter=simsearch2.ffrft&filter=pubt.review
The first link gives its properties.  The second link is a search of biomedical journal articles on the term "dopamine receptor."  I applied two filters, one specifying reviews and the other specifying that the paper must be available free of charge. There are about 2500 articles, which means that if I were researching the topic, I would probably want to apply additional filters.

All the words in the world mean nothing without physical proofs !

[TheBox]

We will take that as a no answer then , you can't detect Dopamine therefore Dopamine is speculation

You can't observe dopamine with a microscope (using a tunneling microscope in very low temperatures it should be definitely possible though, but that's highly impractical), but sure you can detect it.

Same can be said about - say - electrons or magnetic fields, so by your logic they don't exist as well.

Dopamine is a compound with a well known properties, one that we know how to synthesize, how to separate, one that you can buy (as a hydrochloride) salt, one that is used intravenously as a medication in some cases. You really think it is all speculation?

You can prove me wrong by providing a picture of the ''chemical'' Dopamine of course .

Sure thing, image attached.

I am sorry for double posting this quote but I wanted to provide you with the correct atomic model.Q is the elementary charge grounded by the particle . Q does not expand into space because space has no conductive properties . Different elements are different sized particles , hence a bigger particle has more grounded elementary charge than a smaller particle.  Each particle has a conservation max and a Kmax .  I can tell you using physics about molecular bonds etc . (x0,y0,z0) has zero electrons . (x1,y1,z1,) has 1 electron etc etc ..All particles are also dynamic ,what this means is that although any particle has a conservation Qmax , the particles can temporally store x amount of charge.  This allows for molecular bonds .

[Borek]

Q is the elementary charge grounded by the particle . Q does not expand into space because space has no conductive properties . Different elements are different sized particles , hence a bigger particle has more grounded elementary charge than a smaller particle.  Each particle has a conservation max and a Kmax .  I can tell you using physics about molecular bonds etc . (x0,y0,z0) has zero electrons . (x1,y1,z1,) has 1 electron etc etc ..All particles are also dynamic ,what this means is that although any particle has a conservation Qmax , the particles can temporally store x amount of charge.  This allows for molecular bonds .

Sorry, this is just a word salad, in no way related to what we know about charges, molecules and all stuff in between.

[TheBox]

Q is the elementary charge grounded by the particle . Q does not expand into space because space has no conductive properties . Different elements are different sized particles , hence a bigger particle has more grounded elementary charge than a smaller particle.  Each particle has a conservation max and a Kmax .  I can tell you using physics about molecular bonds etc . (x0,y0,z0) has zero electrons . (x1,y1,z1,) has 1 electron etc etc ..All particles are also dynamic ,what this means is that although any particle has a conservation Qmax , the particles can temporally store x amount of charge.  This allows for molecular bonds .

Sorry, this is just a word salad, in no way related to what we know about charges, molecules and all stuff in between.

It is only word salad because you do not know or understand this information . It is very related to what we know about physics and chemistry .

You have made your reply based on existing information , I also know this information . I'm an expert physicist for good reason and that is because I am/have advanced physics . This information is not yet mainstream .

Dunning and Kruger , ones beleif in their knowledge out weighs their ability.

I do not presume you have Dunning and Kruger because you do seem a clever person . Take my word for it that the atomic model I provided you is correct and the way physics works , proves it correct.

I'm not sure how good your physics knowledge is ,do you understand gravity-A , gravity-B , Eigenstates and transition ?

Here is a brief

Gravity-A : All electrical charge is attracted to particles and this is called the grounding process . In example you are attracted to the ground because the conserved electrical charge of your body is attracted to the particles of the ground .

Gravity-B: Gravity B is the impetus of light , which means the force that makes light move from one position to another .It additionally is the cause of moving bodies through space .

Eigenstate : The state of energy of a particle , a space or a system .

Transition : Changing from one state to another


I truly do understand where you are coming from  but I really need your help to learn chemistry more . I always question the teacher and their knowledge as the aim of science is to keep advancing in knowledge .
You are welcome to think I am a crackpot or anything else but that really would not be true .

Anyway we have drifted off topic now , we was on about the absolute proof of Dopemine .

I asked if you or somebody else could explain the test procedure so I understand it . My mind is still open to the existence of Dopemine but I require more certainty because of my absolute learning style .

By the way , I am going easy on you all because you are mods and you will just ban me if I go hard on this forum with advanced stuff .


We can talk molecules in another thread , I will start one later or add to this if you like . I can tell you in detail how atomic molecules work . (Note not all matter is atoms,proven by atoms can't grow, i'e finger nails grow, they can't be atoms) .   

[TheBox]

Sorry, this is just a word salad, in no way related to what we know about charges, molecules and all stuff in between.

P.s I can draw models too ! I messed up this diagram but I've not been asleep for 27 hrs . I give the Carbon atom 36 electrons instead of 6 . I'm sure you can work out the dimensions of 6 and pick a form .

[TheBox]

I went bed but couldn't leave my error so had to get back up to correct it.Here is the correct dimensional model.

[Corribus]

I think it's safe to say this thread has outlived its usefulness.

[Borek]

I think it's safe to say this thread has outlived its usefulness.

Yep.

Locking.