[Babcock_Hall]

In a month or so, we will be using fuming nitric acid for the first time.  We will nitrate a derivative of thiophene on a small scale (50-100 mg?) based on a similar reaction in the literature.  If it goes well, we will scale the reaction up to 250-500 mg.  We will use oven-dried glassware and a nitrogen atmosphere.
(1) Is there anything special in handling this reagent?
(2) After we open the reagent container, how should we store it?  I was thinking of using a small desiccator with some calcium sulfate (Drierite), to minimize its picking up water.

[rolnor]

I have used it, there is nothing to it except good ventilation and gloves. It's not a problem with moisture.