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Topic: Sysnthesis of acetonides from meso-hydrobenzoin  (Read 3335 times)

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Offline zhilong

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Sysnthesis of acetonides from meso-hydrobenzoin
« on: November 06, 2006, 09:15:31 AM »
Dear sir,

May I know why does the yield of my acetonides from meso-hydrobenzoin, so low... only 9%... ?

Could anyone educate me please...

Offline movies

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Re: Sysnthesis of acetonides from meso-hydrobenzoin
« Reply #1 on: November 06, 2006, 12:52:01 PM »
Think about the product that you would be forming.  What interactions might make this structure difficult to form?  Would that be a problem with one of the chiral diastereomers?

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