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Topic: Jacobsen's hydrolytic resolution  (Read 6847 times)

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Offline GSK

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Jacobsen's hydrolytic resolution
« on: January 20, 2007, 12:42:28 PM »
Can it be used to resolve a small, 4-carbon molecule with a 1,2-acetonide and a 3,4 epoxide? The C-2 is already chirally pure (from mannitol). I want to enrich the C-3

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Offline movies

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Re: Jacobsen's hydrolytic resolution
« Reply #1 on: January 25, 2007, 12:26:35 PM »
I would guess that you could.  That chemistry is very robust.
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