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Topic: something about Amides  (Read 3841 times)

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Offline Farid

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something about Amides
« on: June 05, 2007, 09:39:47 AM »
Hi,
I know  how amides react with sodium hydroxide, but only if it's simple amide like Acetamide, or Urea (carbamide). How about more complicated amides? For example Paracetamol.
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Offline Custos

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Re: something about Amides
« Reply #1 on: June 05, 2007, 09:53:01 PM »
It's exactly the same. Think of Paracetamol as acetamide with an extra bit tacked on to the nitrogen. The reaction proceeds in the same way.
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Offline Farid

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Re: something about Amides
« Reply #2 on: June 06, 2007, 07:23:25 AM »
The same way? When it's simple (CH3COONH2amide - the products are: sodium salt and Ammonia.
 
yes?

But if it's paracetamol :

And generaly - if we have admides like CH3COONH'R?
is it sodium salt as well? But what's going on with this R and nitrogern atom?
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Offline Custos

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Re: something about Amides
« Reply #3 on: June 14, 2007, 01:32:31 AM »
Exactly the same. Just replace one of the hydrogens in your NH3 product by the R group.
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