December 22, 2024, 11:06:24 AM
Forum Rules: Read This Before Posting


« previous next »
Pages: [1]   Go Down

Topic: Alpha-decarboxylation?  (Read 5301 times)

0 Members and 1 Guest are viewing this topic.

Offline Fry

  • Regular Member
  • ***
  • Posts: 60
  • Mole Snacks: +3/-3
Alpha-decarboxylation?
« on: June 10, 2007, 02:41:22 AM »
Well I was looking for a way to eliminate CO2 from Tryptophan.. after kicking off the amine I realized that I couldnt follow through with the decarboxylation step as usual..

How plausible would this reaction sequence be? The mechanism drawn may not be the most ideal but I think you know what Im getting at.

Logged

Offline kiwi

  • Chemist
  • Full Member
  • *
  • Posts: 229
  • Mole Snacks: +20/-0
  • Gender: Male
Re: Alpha-decarboxylation?
« Reply #1 on: June 10, 2007, 06:43:33 AM »
i don't like the mechanism you have drawn - but the biological method for synthesis of this important plant hormone comes from tryptophan too, via a similar transamination/decarboxylation/oxidation sequence:

http://www.arabidopsis.org:1555/ARA/NEW-IMAGE?type=PATHWAY&object=PWY-581&detail-level=3

I am sure there are other synthetic routes too.
Logged

Offline Fry

  • Regular Member
  • ***
  • Posts: 60
  • Mole Snacks: +3/-3
Re: Alpha-decarboxylation?
« Reply #2 on: June 10, 2007, 11:53:18 AM »
Quote from: kiwi on June 10, 2007, 06:43:33 AM
i don't like the mechanism you have drawn

You dont! whats wrong with it?  ;D
Logged
Pages: [1]   Go Up
« previous next »
Sponsored Links