December 23, 2024, 09:40:00 PM
Forum Rules: Read This Before Posting


Topic: synthesis of aspirin  (Read 8902 times)

0 Members and 1 Guest are viewing this topic.

hackerdiety03

  • Guest
synthesis of aspirin
« on: February 02, 2005, 10:59:49 PM »
hello!  I am a chem. major in college.  I recently did an experiment of synthesizing aspirin.  catalysts were used in the beginning process, like pyridine, boron trifluoride methanol, and sulfuric acid.  we later did a recrystallization to measure the pure product of aspirin

MAIN QUESTION: Hydrochloric acid is about as strong a mineral acid as sulfuric acid.  Why would it not be satisfactory catalyst in this reaction?

ANSWER:  HCL is too strong of an acid and would destroy the reactants in the process.  Not sure about my answer.    

 

Offline Mitch

  • General Chemist
  • Administrator
  • Sr. Member
  • *
  • Posts: 5298
  • Mole Snacks: +376/-3
  • Gender: Male
  • "I bring you peace." -Mr. Burns
    • Chemistry Blog
Re:synthesis of aspirin
« Reply #1 on: February 02, 2005, 11:07:59 PM »
Sulfuric acid isn't as nucleophilic as HCl would be an other reason. The answer will depend on what the mechanism is.
« Last Edit: February 02, 2005, 11:08:45 PM by Mitch »
Most Common Suggestions I Make on the Forums.
1. Start by writing a balanced chemical equation.
2. Don't confuse thermodynamic stability with chemical reactivity.
3. Forum Supports LaTex

hackerdiety03

  • Guest
Re:synthesis of aspirin
« Reply #2 on: February 02, 2005, 11:13:53 PM »
Isn't related to how Cl is more electronegative than O?  Won't HCL not carry on the reaction to later make aspirin?

Offline Mitch

  • General Chemist
  • Administrator
  • Sr. Member
  • *
  • Posts: 5298
  • Mole Snacks: +376/-3
  • Gender: Male
  • "I bring you peace." -Mr. Burns
    • Chemistry Blog
Re:synthesis of aspirin
« Reply #3 on: February 02, 2005, 11:21:00 PM »
depends on the mechanism.
Most Common Suggestions I Make on the Forums.
1. Start by writing a balanced chemical equation.
2. Don't confuse thermodynamic stability with chemical reactivity.
3. Forum Supports LaTex

Sponsored Links