[CooLWoLF]

I'm working on some home work and it involves determining if I have diastereomers or enantiomers. My question is do axial or equatorial positions matter in determing these? I have a compound that is completely the same except for one has an axial and the other has a equatorial in the same location on each. That is the only difference.

[Dan]

I have a compound that is completely the same except for one has an axial and the other has a equatorial in the same location on each. That is the only difference.

It depends. Do you have other stereogenic centres present? Is the ring locked of free to flip?
Could you post the structure?